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wholeBrain/wholeBrain_results-ongoing_activity.txt
2013-09-04 10:46:06 -04:00

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Ongoing activity in the neonatal mouse cerebral cortex is characterized by discrete domains

  • Cortical column (mini/meso/super columns) history (20th century anatomists).
  • Column physiology-- Hubel and Wiesel. Rodent V1?
  • Developmental studies-- fetal monkey ODCs.
  • Rodent barrels (early anatomical emergence from TC input, functional/physiological emergence?). * What is known about columns/domains in secondary/association/non-primary sensory representations? Rest of rodent S1 (non-barrel cortex?).
  • Calcium domains of Yuste, Science 1992 paper.
  • Other slice calcium recordings, patch/gap junctions. In vivo physiology? (Not too many multisite electrode recordings in cortex, spatial resolution issue).
  • Calcium imaging-- Konnerth 'waves' in Ent cortex. For visual cortex, domains activity in extrastriate cortex (Ackman Nature 2012). But S1-- Golshani work in later postnatal-- but activity not obeying domains in barrel cortex-- problem with spatial sampling in the xy and the z for this study?

Domains:

Domain overlay:

Domain stats:

key value unit
xmean 388.6234 µm
ymean 394.9717 µm
zmean 0.63622 s
xmax 3178 µm
ymax 2383.5 µm
zmax 14.6 s
xmin 11.35 µm
ymin 22.7 µm
zmin 0.2 s

2.8683 domains/sec

Temporal correlation of activity between the hemispheres: